powerful Performance Constructed with powerful probiotic microorganisms such as Lactobacillus and Yeast. Microorganisms of BIO-BOSS can multiply rapidly in animal gut unlike other probiotic products because these are directly cultured in the manure. Easy to use It is the unique freeze-dried anaerobic vial product and its solubility is very high with small quantity of water (any kinds of water). Then, it can be applied through the nipple without any blocking of water pipeline. Antibiotic Competence BIO-BOSS is compatible with the major antibiotics up to a concentration of 500 §¶/ml. BIO-BOSS, therefore, can be used with most of the antibiotics commonly used.